• Tablets (Green Dragon Botanicals): These are normally labeled as resveratrol on the bottle. Resveratol, the major constituent in Knotweed is quite healthful. The assistance of a qualified health care provider familiar with all dosage outlines, contraindications, and herb/drug interactions outlined in Healing Lyme, and familar with your personal health history and current symptoms is strongly suggested. Brandon: That is 8g of knotweed per day at the max dose… so just weigh out 8 grams and take in divided doses if you can. Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. I could use the Vitamix first, but the wife would get mad because it would destroy the inside finish. So at his max dosage I am gathering 10 grams of knotweed per day. Avoid use during lactation; information regarding use during lactation is lacking. Thanks. Yeah, it’s a lot of work. all the best Lyme Disease: Japanese Knotweed root is known to aid the central nervous system and kill Lyme bacteria. The plant is native to eastern Asia, including Japan, China, and Korea. The LD50 of emodin and polydatin is 250 and 1,000 mg/kg, respectively. Japanese knotweed root (Polygonum cuspidatum) – • Root powder: 1 tsp – 1 TBS 3x daily. Hi Julia. My homestead specializes in growing organic Japanese Knotweed. That is just suggested as a range. I want to do the protocol that Buhner recommends but unsure how to proceed. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I am a medical herbalist and am currently working with a Gp in the Uk . Studies in rats and mice have shown antioxidant properties of P. cuspidatum that are generally attributed to the chemical constituents of resveratrol, polydatin, piceatannol, and anthraquinones and stilbenes.Kim 2010, Peng 2013, Piotrowska 2012, Zhang 2012 Carbon tetrachloride–induced liver injury and induced acute cerebral ischemia were reduced by oral extracts of P. cuspidatum.Kim 2010, Zhang 2012 In models of vascular dementia and Parkinson disease in rats, P. cuspidatum extract and polydatin administered orally resulted in improved cognitive and behavioral measures and increased antioxidant capacity in the relevant tissues.Li 2012, Wang 2011. Vertigo, candida, and classic MS symptoms. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Other than that I can’t believe what’s happening. He recommended 1-4 tabs 3-4 times a day. Thank you for pointing this out. Eleutherococcus – 4200 mg per day = 6 capsules Note- I took a 2 week break every 60 days. 1 tsp (1.2g) – 1.5 tbs/4.5 tsp (8.4g) daily. Something abs weren’t doing. I don’t want to wipe it out, just stop it killing me or driving me mad as it wipes ‘me’ out. There is much to know about treating Lyme Disease and how this plant root works within the body. I would really appreciate and links of research on this. If 1 tsp. You should talk with your health care provider for complete information about the risks and benefits of using this product. On the bright side, I’ve had this non stop swollen lingual tonsil that’s been shutting off my airways for the last 6 mos and that’s finally going down. Avoid in pregnancy. How does that taste, btw? Thanks for your help. As to the dose, yes, at the highest dose that would be 16 capsules per day. Lisa, I’m not a doctor, but I would honestly stop all of them, and add one back at a time, giving a few days in between.. To figure out your reaction issues. Because of the plant's spreading rhizomes, P. cuspidatum is grown commercially as a major source for resveratrol production (see Resveratrol monograph), while also being considered a noxious, invasive class B or C weed in certain US states.Chen 2013, Peng 2013, USDA 2013, At least 100 prescriptions using the root exist in the Pharmacopoeia of the People's Republic of China to treat bronchitis and cough, gonorrhea, inflammation, infection, jaundice, hyperlipidemia and hypertension, menopausal symptoms and amenorrhea, and skin burns. Thirteen years ago I dealt with lyme disease and it went into remission. Really good and important addendum Brandon. Start at the lower dose and work up, OR . Nothing in this column is intended to replace the expertise and care of a qualified health care practitioner. It enhances and modulates immune function, is active against a number of bacteria, is anti-inflammatory for both bacterial and arthritic inflammations, and protects the body against endotoxin damage. Knotweed grows across the stream in my backyard, so I too “specialize” in growing it. I have the regular symptoms, but have also had a second EM with no puncture mark. During Lyme infection, for instance, there is a spirochete-stimulated release of a number of matrix metalloptroteinases (MMPs) which occurs through a particular grouping of pathways.